Oncotarget distinguishes itself from most other journals because it is a peer-reviewed, international journal, which publishes content on all topics about cancer: the pathology, therapy and treatment options, and patient perspectives regarding their satisfaction of therapies and quality of life.
With the primary focus on a topic as broad as cancer research, papers are accepted from many subjects including age-related diseases, immunology, pathology, endocrinology, and immunology. Ranked in 2015 by Total Documents as the leader of all journals in Oncology, the freely-accessed journal is edited by the well-respected Dr. Michael Blagosklonny and Dr. Andrei Gudkov of the Roswell Park Cancer Institute in Buffalo, NY. Scheduling publishings on a weekly basis, exceptions are sometimes made for special demands and issues.
Blagosklonny and Gudkov created Oncotarget with two goals in mind: to publish scientific results in a timely fashion and circulate them openly, making it possible for everyone to access the information. The ultimate goal of encouraging rapid publication is to eliminate all diseases one day, say Blagosklonny and Gudkov. Source: http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path=718&path=1089
The positive feedback that Oncotarget has received has prompted them to accept papers from topics beyond just oncology. These subjects now include microbiology, pathology, endocrinology, metabolism, cell and molecular biology, pharmacology, neuropathology, cardiology, and aging. Recently, a study was published in Oncotarget regarding the use of e-cigarettes and their negative effects on oral health. The study was led by Irfan Rahman, Ph.D., professor of Environmental Medicine at the University of Rochester School of Medicine and Dentistry. He led his team to investigate the first study that addressed the damage that is done to one’s oral health on a cellular and molecular level upon consumption of e-cigarettes. Rahman’s study was funded by the National Institutes of Health, and his collaborators were from the University of Rochester and Stony Brook University, both in New York. Because e-cigarettes are viewed as safer alternatives to traditional cigarettes, they have risen in popularity among current and formers smokers as well among the young adult population. However, new data suggests otherwise; they are not as safe as advertised.
Rahman and his team found that when healthy gum tissue was exposed to vapors of e-cigarettes, an inflammatory and stress response was triggered. While inflammatory responses prompt tissues to heal in the body, it is less likely to happen in gum tissue, and consequently, the affected gum tissue dies. Over time, receding gums, which may seem trivial, will lead to bone and tooth loss. That was not all; the team also found inflammation-propagated damage to DNA in the gum tissue upon closer observation. Changes to DNA can pose a more severe threat to health including increased risk of various cancers. What is responsible for causing this change in DNA? It is proposed by Rahman and team that the flavoring chemicals in e-cigarettes are behind the reason for extensive damage to cells in the mouth. Nicotine, a key ingredient in both e-cigarettes and conventional cigarettes, is a stimulant that gives a euphoric-like feeling, or high, to users. The gum tissue becomes damaged when exposed to nicotine because the blood vessels surrounding gums become restricted, providing the inadequate nutrition needed to maintain healthy gums. Rahman mentions that while this is an initial study and that more research is needed on this topic, he encourages consumers to educate themselves on the potential risks and dangers of e-cigarettes.
Review a publishing via Oncotarget on Impact Journals